Endocrine Abstracts

Introduction: Ocular changes and ocular symptoms may be encountered in patients with hypothyroidism and hyperthyroidism. However, the data concerning the effects of thyroid disorders on intraocular pressure (IOP), central corneal thickness (CCT), and retinal thickness (RT) are very rare. Here, we aimed to evaluate the alterations in IOP, CCT, and RT in patients with euthyroid autoimmune thyroiditis (AIT).Methods: Twenty-five subjects with euthyroid AIT w...

The classic clinic manifestation of primary hyperparathyroidism (PHPT) is osteitis fibrosa cystica, a severe skeletal disease characterized by brown tumors, bone cysts and deformities, due to extremely elevated bone resorption elicited by continuously high parathyroid hormone (PTH) levels. In cardiovascular system there may be shortened QT interval, deposition of calcium in heart valves, coronary arteries, and myocardial fibers. Here, we report a case with PHPT, who have anore...

Aim: Contradictory results in limited number of studies were reported about the effects of Ramadan fasting on thyroid hormones. We aimed to evaluate the thyroid functions in Ramadan, and compare late evening or pre-sahour use of levothyroxine in patients being treated for hypothyroidism.Methods: Patients taking levothyroxine for hypothyroidism who were seen in the last one week before Ramadan (8–15 May 2018) and had normal thyroid functions were rec...

Aim: Atypia/follicular lesion of undetermined significance(AUS/FLUS) is a category of thyroid cytology with features that are neither definitely benign or malignant. We aimed to determine whether specific cytologic or architectural features are associated with malignancy in AUS/FLUS category of Bethesda system according to subgroups.Methods: The specimens of patients who underwent surgery with preoperative thyroid fine neeedle aspiration (FNA) biopsies o...

Introduction: Ocular changes are common in various endocrine disorders. However, there are only few studies reporting ocular changes in patients with primary hyperparathyroidism (PHPT). Here, we examined central corneal thickness (CCT) and retinal thickness (RT), intraocular pressure (IOP) and their relationships with serum intact parathyroid hormone (iPTH), calcium (Ca), and phosphorus levels in PHPT patients.Methods: Thirty-seven patients with PHPT wer...

Introduction: Reoperative surgery for thyroid disease is rare. It is sometimes indicated for nodular recurrence after partial surgery for initially benign thyroid disease or for a completion total thyroidectomy when a final diagnosis of thyroid cancer is confirmed on a permanent section of a partially removed thyroid gland. We aimed to investigate the demographic features and reoperation indications in patients with reoperative thyroidectomy.Methods: Thi...

Introduction: Radioactive iodine (RAI) therapy is widely used in the treatment of hyperthyroidism especially in patients with Graves’ disease (GD), toxic multinodular goitre (TMNG), and toxic adenoma. RAI may lead to worsening of the autoimmunity with the elevation of TSH-receptor antibody (TRAB). In this study, we aimed to compare the effects of surgery or RAI treatment on TRAB.Methods: Hyperthyroid patients were divided into three groups; patients...

Atypical tumors were identified in 15% of pituitary adenomas, and they tended to be aggressive, invasive macroadenomas. WHO classification of atypical pituitary adenomas include; Ki-67 proliferative index >3%, excessive p53 immunoreactivity, and ≥ 2 mitotic figures per 10 high-powered fields. Pituitary carcinomas are extremely rare tumors with cerebrospinal or extracranial metastasis.Case: A 31 years old man with symptoms of stuffy nose and sno...

Introduction: Fine needle aspiration cytology (FNAC) has been widely accepted the most accurate, safe and cost-effective method for evaluation of the thyroid nodules. The most challenging category in the FNAC is atypia of undetermined significance (AUS) and follicular lesion of undetermined significance (FLUS). Bethesda System (BS) recommends repeat FNAC in that category due to their low risk of malignancy. In our study, we aimed to investigate the malignancy rate of thyroid n...

Introduction: ‘Artificial intelligence’ is an information-processing technology developed and inspired by the information processing technique of human brain. Artificial intelligence applications are used with an increasing ratio in medicine; particularly in the fields of breast cancer, radiology, cardiology, health management and drug effects analysis. There is not any study concerning thyroid diseases and artificial intelligence applications in the literature. In t...